Brian Castle publishes in Molecular Biology of the Cell

Brian's paper titled Mechanisms of kinetic stabilization by the drugs paclitaxel and vinblastine was accepted at Molecular Biology of the Cell! In this study, along with co-authors from University of Michigan, we use high-resolution imaging of microtubules in epithelial cells and in vitro using purified protein, and a computational model of microtubule self-assembly dynamics to determine how widely-used chemotherapy drugs affect the kinetics and thermodynamics of microtubule assembly. Great work, Brian!

Brian Castle